VaidhyaMegha is building an open knowledge graph on clinical trials, comprising

• Clinical trial ids from across the globe
• MeSH ids for
  • Symptoms/Phenotype
  • Diseases
• PubMed Article ids
• Genotype(from Human Genome),

Specification

Below is a very brief specification

• Inputs
  • Mesh RDF
  • WHO’s clinical trials database – ICTRP.
  • US clinical trial registrydata from CTTI’s AACT database.
  • Data from clinical trial registries across the globe scraped from their websites’ ex: India
  • MEDLINE Co-Occurrences (MRCOC) Files
• Outputs
  • Clinical Trials RDF with below constituent ids and their relationships
    • MeSH, Clinical Trial, PubMed Article, Symptom/Phenotype, Genotype(from Human Genome)
    • Additionally, clinical trial -> clinical trial links across trial registries will also be discovered and added.

Source code

• Source code would be hosted here.

Release notes

v0.2 : 27-Jan-2022

• Clinical trials are linked to the RDF nodes corresponding to the MeSH terms for conditions.
• Download the enhanced RDF from here.

Reference

VaidhyaMegha’s prior work on

• clinical trial registries data linking.
• symptoms to diseases linking.
• phenotype to genotype linking.
• trials to research articles linking.

Last 3 are covered in the examples folder. They were covered in prior work in separate public repos.